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Document type:
journal article 
Author(s):
Nieberler, Markus; Reuning, Ute; Reichart, Florian; Notni, Johannes; Wester, Hans-Jürgen; Schwaiger, Markus; Weinmüller, Michael; Räder, Andreas; Steiger, Katja; Kessler, Horst 
Title:
Exploring the Role of RGD-Recognizing Integrins in Cancer. 
Abstract:
Integrins are key regulators of communication between cells and with their microenvironment. Eight members of the integrin superfamily recognize the tripeptide motif Arg-Gly-Asp (RGD) within extracelluar matrix (ECM) proteins. These integrins constitute an important subfamily and play a major role in cancer progression and metastasis via their tumor biological functions. Such transmembrane adhesion and signaling receptors are thus recognized as promising and well accessible targets for novel dia...    »
 
Journal title abbreviation:
Cancers (Basel) 
Year:
2017 
Journal volume:
Journal issue:
Language:
eng 
Fulltext / DOI:
TUM Institution:
Klinik und Poliklinik für Mund-, Kiefer- und Gesichtschirurgie; Klinik und Poliklinik für Frauenheilkunde; Klinik und Poliklinik für Nuklearmedizin; Institut für Allgemeine Pathologie und pathologische Anatomie