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Dokumenttyp:
journal article 
Autor(en):
Moon, Jisook; Schwarz, Sigrid C; Lee, Hyun-Seob; Kang, Jun Mo; Lee, Young-Eun; Kim, Bona; Sung, Mi-Young; Höglinger, Günter; Wegner, Florian; Kim, Jin Su; Chung, Hyung-Min; Chang, Sung Woon; Cha, Kwang Yul; Kim, Kwang-Soo; Schwarz, Johannes 
Titel:
Preclinical Analysis of Fetal Human Mesencephalic Neural Progenitor Cell Lines: Characterization and Safety In Vitro and In Vivo. 
Abstract:
We have developed a good manufacturing practice for long-term cultivation of fetal human midbrain-derived neural progenitor cells. The generation of human dopaminergic neurons may serve as a tool of either restorative cell therapies or cellular models, particularly as a reference for phenotyping region-specific human neural stem cell lines such as human embryonic stem cells and human inducible pluripotent stem cells. We cultivated 3 different midbrain neural progenitor lines at 10, 12, and 14 we...    »
 
Zeitschriftentitel:
Stem Cells Transl Med 
Jahr:
2017 
Band / Volume:
Heft / Issue:
Seitenangaben Beitrag:
576-588 
Sprache:
eng 
Print-ISSN:
2157-6564 
TUM Einrichtung:
Neurologische Klinik und Poliklinik