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Dokumenttyp:
journal article 
Autor(en):
Kiechle, Marion; Engel, Christoph; Berling, Anika; Hebestreit, Katrin; Bischoff, Stephan; Dukatz, Ricarda; Gerber, Wolf-Dieter; Siniatchkin, Michael; Pfeifer, Katharina; Grill, Sabine; Yahiaoui-Doktor, Maryam; Kirsch, Ellen; Niederberger, Uwe; Marter, Nicole; Enders, Ute; Löffler, Markus; Meindl, Alfons; Rhiem, Kerstin; Schmutzler, Rita; Erickson, Nicole; Halle, Martin 
Titel:
Lifestyle intervention in BRCA1/2 mutation carriers: study protocol for a prospective, randomized, controlled clinical feasibility trial (LIBRE-1 study). 
Abstract:
Women with highly penetrant BRCA mutations have a 55-60% lifetime risk for breast cancer and a 16-59% lifetime risk for ovarian cancer. However, penetrance differs interindividually, indicating that environmental and behavioral factors may modify this risk. These include lifestyle factors such as physical activity status, dietary habits, and body weight. The modification of penetrance by changing lifestyle factors has not thus far been investigated in a randomized trial in BRCA mutation carriers...    »
 
Zeitschriftentitel:
Pilot Feasibility Stud 
Jahr:
2016 
Band / Volume:
Seitenangaben Beitrag:
74 
Sprache:
eng 
Print-ISSN:
2055-5784 
TUM Einrichtung:
Lehrstuhl und Poliklinik für präventive und rehabilitative Sportmedizin