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Dokumenttyp:
journal article 
Autor(en):
Eicher, John D; Chami, Nathalie; Kacprowski, Tim; Nomura, Akihiro; Chen, Ming-Huei; Yanek, Lisa R; Tajuddin, Salman M; Schick, Ursula M; Slater, Andrew J; Pankratz, Nathan; Polfus, Linda; Schurmann, Claudia; Giri, Ayush; Brody, Jennifer A; Lange, Leslie A; Manichaikul, Ani; Hill, W David; Pazoki, Raha; Elliot, Paul; Evangelou, Evangelos; Tzoulaki, Ioanna; Gao, He; Vergnaud, Anne-Claire; Mathias, Rasika A; Becker, Diane M; Becker, Lewis C; Burt, Amber; Crosslin, David R; Lyytikäinen, Leo-Pekka; N...    »
 
Titel:
Platelet-Related Variants Identified by Exomechip Meta-analysis in 157,293 Individuals. 
Abstract:
Platelet production, maintenance, and clearance are tightly controlled processes indicative of platelets' important roles in hemostasis and thrombosis. Platelets are common targets for primary and secondary prevention of several conditions. They are monitored clinically by complete blood counts, specifically with measurements of platelet count (PLT) and mean platelet volume (MPV). Identifying genetic effects on PLT and MPV can provide mechanistic insights into platelet biology and their role in...    »
 
Zeitschriftentitel:
Am J Hum Genet 
Jahr:
2016 
Band / Volume:
99 
Heft / Issue:
Seitenangaben Beitrag:
40-55 
Sprache:
eng 
Print-ISSN:
0002-9297 
TUM Einrichtung:
Klinik für Herz- und Kreislauferkrankungen