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Dokumenttyp:
journal article 
Autor(en):
Xu, Kai; Kuntz, Lara A; Foehr, Peter; Kuempel, Katharina; Wagner, Alexandra; Tuebel, Jutta; Deimling, Constantin V; Burgkart, Rainer H 
Titel:
Efficient decellularization for tissue engineering of the tendon-bone interface with preservation of biomechanics. 
Abstract:
Interfaces between tendon/ligament and bone ("entheses") are highly specialized tissues that allow for stress transfer between mechanically dissimilar materials. Entheses show very low regenerative capacity resulting in high incidences of failure after surgical repair. Tissue engineering is a promising approach to recover functionality of entheses. Here, we established a protocol to decellularize porcine entheses as scaffolds for enthesis tissue engineering. Chemical detergents as well as physic...    »
 
Zeitschriftentitel:
PLoS ONE 
Jahr:
2017 
Band / Volume:
12 
Heft / Issue:
Seitenangaben Beitrag:
e0171577 
Sprache:
eng 
TUM Einrichtung:
Orthopädische und Sportorthopädische Klinik und Poliklinik