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Dokumenttyp:
journal article 
Autor(en):
Worst, Barbara C; van Tilburg, Cornelis M; Balasubramanian, Gnana Prakash; Fiesel, Petra; Witt, Ruth; Freitag, Angelika; Boudalil, Miream; Previti, Christopher; Wolf, Stephan; Schmidt, Sabine; Chotewutmontri, Sasithorn; Bewerunge-Hudler, Melanie; Schick, Matthias; Schlesner, Matthias; Hutter, Barbara; Taylor, Lenka; Borst, Tobias; Sutter, Christian; Bartram, Claus R; Milde, Till; Pfaff, Elke; Kulozik, Andreas E; von Stackelberg, Arend; Meisel, Roland; Borkhardt, Arndt; Reinhardt, Dirk; Klusmann,...    »
 
Titel:
Next-generation personalised medicine for high-risk paediatric cancer patients - The INFORM pilot study. 
Abstract:
The'Individualized Therapy for Relapsed Malignancies in Childhood' (INFORM) precision medicine study is a nationwide German program for children with high-risk relapsed/refractory malignancies, which aims to identify therapeutic targets on an individualised basis. In a pilot phase, reported here, we developed the logistical and analytical pipelines necessary for rapid and comprehensive molecular profiling in a clinical setting. Fifty-seven patients from 20 centers were prospectively recruited. M...    »
 
Zeitschriftentitel:
Eur J Cancer 
Jahr:
2016 
Band / Volume:
65 
Seitenangaben Beitrag:
91-101 
Sprache:
eng 
Print-ISSN:
0959-8049 
TUM Einrichtung:
Kinderklinik und Poliklinik