Benutzer: Gast  Login
Dokumenttyp:
journal article 
Autor(en):
Kuhn, Marion; Wolf, Elias; Maier, Jonathan G; Mainberger, Florian; Feige, Bernd; Schmid, Hanna; Bürklin, Jan; Maywald, Sarah; Mall, Volker; Jung, Nikolai H; Reis, Janine; Spiegelhalder, Kai; Klöppel, Stefan; Sterr, Annette; Eckert, Anne; Riemann, Dieter; Normann, Claus; Nissen, Christoph 
Titel:
Sleep recalibrates homeostatic and associative synaptic plasticity in the human cortex. 
Abstract:
Sleep is ubiquitous in animals and humans, but its function remains to be further determined. The synaptic homeostasis hypothesis of sleep-wake regulation proposes a homeostatic increase in net synaptic strength and cortical excitability along with decreased inducibility of associative synaptic long-term potentiation (LTP) due to saturation after sleep deprivation. Here we use electrophysiological, behavioural and molecular indices to non-invasively study net synaptic strength and LTP-like plast...    »
 
Zeitschriftentitel:
Nat Commun 
Jahr:
2016 
Band / Volume:
Seitenangaben Beitrag:
12455 
Sprache:
eng 
TUM Einrichtung:
Kinderklinik und Poliklinik