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Dokumenttyp:
journal article 
Autor(en):
Erlmeier, F; Seitz, A K; Hatzichristodoulou, G; Stecher, L; Retz, M; Gschwend, J E; Weichert, W; Kübler, H R; Horn, T 
Titel:
The Role of PD-L1 Expression and Intratumoral Lymphocytes in Response to Perioperative Chemotherapy for Urothelial Carcinoma. 
Abstract:
Introduction: Immunological pathways are relevant for the effectiveness of conventional cytotoxic chemotherapy. Recently, checkpoint inhibition of the PD-1/PD-L1 axis has been shown to be therapeutically relevant in urothelial carcinoma. Objective: To monitor PD-L1 expression on tumor cells and intratumoral infiltration with CD8 positive lymphocytes during perioperative chemotherapy for urothelial cancer and to evaluate their use as potential predictive markers for chemotherapy. Patients and Met...    »
 
Zeitschriftentitel:
Bladder Cancer 
Jahr:
2016 
Band / Volume:
Heft / Issue:
Seitenangaben Beitrag:
425-432 
Sprache:
eng 
Print-ISSN:
2352-3727 
TUM Einrichtung:
Institut für Allgemeine Pathologie und pathologische Anatomie; Urologische Klinik und Poliklinik