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Dokumenttyp:
journal article 
Autor(en):
Bonabi, SY; El-Hamad, F; Muller, A; Dommasch, M; Steger, A; Schmidt, G; Baumert, M 
Titel:
Recording duration and short-term reproducibility of heart rate and QT interval variability in patients with myocardial infarction 
Abstract:
Beat-to-beat variability of the QT interval (QTV) measured on surface ECG has emerged as a potential marker for ventricular repolarization instability and has been used along with heart rate variability (HRV) to predict arrhythmic risk. Since measurement modalities of QTV have not been standardized, the objective of this study was to investigate the effect of ECG recording duration on QTV as well as HRV. Using a database of 30 min ECG recorded from 500 patients with acute myocardial infraction during rest, we extracted RR and QT interval time series and estimated different HRV and QTV metrics over windows of varying length. Analysis of variance (ANOVA) and intraclass correlation analyses were computed to investigate the effect of recording length on consistency and short-term reproducibility of HRV and QTV variables. Good consistency (non-significant ANOVA results) and short-term reproducibility (intra-class correlation coefficients> 0.8) were demonstrated for all but standard deviation based metrics when at least 200 beats were included in the estimation. In conclusion, QTV can be quantified from resting ECG with good short-term consistency and reproducibility that is comparable to that of HRV. 
Zeitschriftentitel:
Physiol Meas 
Jahr:
2016 
Band / Volume:
37 
Heft / Issue:
11 
Seitenangaben Beitrag:
1925-1933 
Sprache:
eng 
Print-ISSN:
0967-3334 
TUM Einrichtung:
I. Medizinische Klinik und Poliklinik