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Document type:
journal article 
Author(s):
Liu, Zhen; Jian, Ziying; Wang, Qian; Cheng, Tao; Feuerecker, Benedikt; Schwaiger, Markus; Huang, Sung-Cheng; Ziegler, Sibylle I; Shi, Kuangyu 
Title:
A Continuously Infused Microfluidic Radioassay System for the Characterization of Cellular Pharmacokinetics. 
Abstract:
Measurement of cellular tracer uptake is widely applied to learn the physiologic status of cells and their interactions with imaging agents and pharmaceuticals. In-culture measurements have the advantage of less stress to cells. However, the tracer solution still needs to be loaded, unloaded, and purged from the cell culture during the measurements. Here, we propose a continuously infused microfluidic radioassay (CIMR) system for continuous in-culture measurement of cellular uptake. The system w...    »
 
Journal title abbreviation:
J Nucl Med 
Year:
2016 
Journal volume:
57 
Journal issue:
10 
Pages contribution:
1548-1555 
Language:
eng 
Print-ISSN:
0161-5505 
TUM Institution:
Nuklearmedizinische Klinik und Poliklinik