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Document type:
journal article 
Author(s):
Dzien, Piotr; Fages, Anne; Jona, Ghil; Brindle, Kevin M; Schwaiger, Markus; Frydman, Lucio 
Title:
Following Metabolism in Living Microorganisms by Hyperpolarized (1)H NMR. 
Abstract:
Dissolution dynamic nuclear polarization (dDNP) is used to enhance the sensitivity of nuclear magnetic resonance (NMR), enabling monitoring of metabolism and specific enzymatic reactions in vivo. dDNP involves rapid sample dissolution and transfer to a spectrometer/scanner for subsequent signal detection. So far, most biologically oriented dDNP studies have relied on hyperpolarizing long-lived nuclear spin species such as (13)C in small molecules. While advantages could also arise from observing...    »
 
Journal title abbreviation:
J Am Chem Soc 
Year:
2016 
Journal volume:
138 
Journal issue:
37 
Pages contribution:
12278-86 
Language:
eng 
Fulltext / DOI:
Print-ISSN:
0002-7863 
TUM Institution:
Nuklearmedizinische Klinik und Poliklinik