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Dokumenttyp:
journal article 
Autor(en):
D'Alessandria, Calogero; Braesch-Andersen, Sten; Bejo, Kristel; Reder, Sybille; Blechert, Birgit; Schwaiger, Markus; Bartolazzi, Armando 
Titel:
Noninvasive In Vivo Imaging and Biologic Characterization of Thyroid Tumors by ImmunoPET Targeting of Galectin-3. 
Abstract:
The high prevalence of thyroid nodules in the adult population and the relatively low incidence of thyroid cancer make the preoperative identification of malignant lesions challenging. The ?-galactoside-binding protein galectin-3 is widely expressed in well-differentiated thyroid carcinomas, but not in normal thyrocytes and benign thyroid nodules. This molecule offers a candidate biomarker to improve thyroid cancer diagnosis. Here we report the development of an immunoPET approach for noninvasiv...    »
 
Zeitschriftentitel:
Cancer Res 
Jahr:
2016 
Band / Volume:
76 
Heft / Issue:
12 
Seitenangaben Beitrag:
3583-92 
Sprache:
eng 
Print-ISSN:
0008-5472 
TUM Einrichtung:
Nuklearmedizinische Klinik und Poliklinik