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Document type:
journal article 
Author(s):
Jörger, Ann-Kathrin; Liu, Lei; Fehlner, Karin; Weisser, Tanja; Cheng, Zhangjun; Lu, Miao; Höchst, Bastian; Bolzer, Andreas; Wang, Baocai; Hartmann, Daniel; Assfalg, Volker; Sunami, Yoshiaki; Schlitter, Anna Melissa; Friess, Helmut; Hüser, Norbert; Laschinger, Melanie 
Title:
Impact of NKT Cells and LFA-1 on Liver Regeneration under Subseptic Conditions. 
Abstract:
Activation of the immune system in terms of subseptic conditions during liver regeneration is of paramount clinical importance. However, little is known about molecular mechanisms and their mediators that control hepatocyte proliferation. We sought to determine the functional role of immune cells, especially NKT cells, in response to partial hepatectomy (PH), and to uncover the impact of the integrin lymphocyte function-associated antigen-1 (LFA-1) on liver regeneration in a subseptic setting.Wi...    »
 
Journal title abbreviation:
PLoS ONE 
Year:
2016 
Journal volume:
11 
Journal issue:
12 
Pages contribution:
e0168001 
Language:
eng 
TUM Institution:
Chirurgiesche Klinik und Poliklinik; Institut für Molekulare Immunologie; Institut für Allgemeine Pathologie und pathologische Anatomie