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Dokumenttyp:
journal article 
Autor(en):
Hedegaard, Jakob; Lamy, Philippe; Nordentoft, Iver; Algaba, Ferran; Høyer, Søren; Ulhøi, Benedicte Parm; Vang, Søren; Reinert, Thomas; Hermann, Gregers G; Mogensen, Karin; Thomsen, Mathilde Borg Houlberg; Nielsen, Morten Muhlig; Marquez, Mirari; Segersten, Ulrika; Aine, Mattias; Höglund, Mattias; Birkenkamp-Demtröder, Karin; Fristrup, Niels; Borre, Michael; Hartmann, Arndt; Stöhr, Robert; Wach, Sven; Keck, Bastian; Seitz, Anna Katharina; Nawroth, Roman; Maurer, Tobias; Tulic, Cane; Simic, Tatjan...    »
 
Titel:
Comprehensive Transcriptional Analysis of Early-Stage Urothelial Carcinoma. 
Abstract:
Non-muscle-invasive bladder cancer (NMIBC) is a heterogeneous disease with widely different outcomes. We performed a comprehensive transcriptional analysis of 460 early-stage urothelial carcinomas and showed that NMIBC can be subgrouped into three major classes with basal- and luminal-like characteristics and different clinical outcomes. Large differences in biological processes such as the cell cycle, epithelial-mesenchymal transition, and differentiation were observed. Analysis of transcript v...    »
 
Zeitschriftentitel:
Cancer Cell 
Jahr:
2016 
Band / Volume:
30 
Heft / Issue:
Seitenangaben Beitrag:
27-42 
Sprache:
eng 
Print-ISSN:
1535-6108 
TUM Einrichtung:
Urologische Klinik und Poliklinik