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Document type:
journal article 
Author(s):
Erlmeier, F; Seitz, A K; Hatzichristodoulou, G; Stecher, L; Retz, M; Gschwend, J E; Weichert, W; Kübler, H R; Horn, T 
Title:
The Role of PD-L1 Expression and Intratumoral Lymphocytes in Response to Perioperative Chemotherapy for Urothelial Carcinoma. 
Abstract:
Introduction: Immunological pathways are relevant for the effectiveness of conventional cytotoxic chemotherapy. Recently, checkpoint inhibition of the PD-1/PD-L1 axis has been shown to be therapeutically relevant in urothelial carcinoma. Objective: To monitor PD-L1 expression on tumor cells and intratumoral infiltration with CD8 positive lymphocytes during perioperative chemotherapy for urothelial cancer and to evaluate their use as potential predictive markers for chemotherapy. Patients and Met...    »
 
Journal title abbreviation:
Bladder Cancer 
Year:
2016 
Journal volume:
Journal issue:
Pages contribution:
425-432 
Language:
eng 
Print-ISSN:
2352-3727 
TUM Institution:
Urologische Klinik und Poliklinik