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Dokumenttyp:
journal article 
Autor(en):
Schwartz, Michael W; Seeley, Randy J; Tschöp, Matthias H; Woods, Stephen C; Morton, Gregory J; Myers, Martin G; D'Alessio, David 
Titel:
Cooperation between brain and islet in glucose homeostasis and diabetes. 
Abstract:
Although a prominent role for the brain in glucose homeostasis was proposed by scientists in the nineteenth century, research throughout most of the twentieth century focused on evidence that the function of pancreatic islets is both necessary and sufficient to explain glucose homeostasis, and that diabetes results from defects of insulin secretion, action or both. However, insulin-independent mechanisms, referred to as'glucose effectiveness', account for roughly 50% of overall glucose disposal,...    »
 
Zeitschriftentitel:
Nature 
Jahr:
2013 
Band / Volume:
503 
Heft / Issue:
7474 
Seitenangaben Beitrag:
59-66 
Sprache:
eng 
Print-ISSN:
0028-0836 
TUM Einrichtung:
Fakultät für Medizin (zentral angehängte Professuren und Einrichtungen: Profs. Tschöp, Berberat; TUMCells, ZPF, MSZ)