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Document type:
journal article 
Author(s):
Schwartz, Michael W; Seeley, Randy J; Tschöp, Matthias H; Woods, Stephen C; Morton, Gregory J; Myers, Martin G; D'Alessio, David 
Title:
Cooperation between brain and islet in glucose homeostasis and diabetes. 
Abstract:
Although a prominent role for the brain in glucose homeostasis was proposed by scientists in the nineteenth century, research throughout most of the twentieth century focused on evidence that the function of pancreatic islets is both necessary and sufficient to explain glucose homeostasis, and that diabetes results from defects of insulin secretion, action or both. However, insulin-independent mechanisms, referred to as'glucose effectiveness', account for roughly 50% of overall glucose disposal,...    »
 
Journal title abbreviation:
Nature 
Year:
2013 
Journal volume:
503 
Journal issue:
7474 
Pages contribution:
59-66 
Language:
eng 
Print-ISSN:
0028-0836 
TUM Institution:
Fakultät für Medizin (zentral angehängte Professuren und Einrichtungen: Profs. Tschöp, Berberat; TUMCells, ZPF, MSZ)