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Document type:
journal article 
Author(s):
Liermann, Jakob; Naumann, Patrick; Fortunato, Franco; Schmid, Thomas E; Weber, Klaus-Josef; Debus, Jürgen; Combs, Stephanie E 
Title:
Phytotherapeutics Oridonin and Ponicidin show Additive Effects Combined with Irradiation in Pancreatic Cancer . 
Abstract:
Chemoradiation of locally advanced non-metastatic pancreatic cancer can lead to secondary operability by tumor mass reduction. Here, we analyzed radiomodulating effects of oridonin and ponicidin in pancreatic cancer . Both agents are ent-kaurane diterpenoids, extracted from , a plant that is well known in Traditional Chinese Medicine. Cytotoxic effects have recently been shown in different tumor entities for both agents.Pancreatic cancer cell lines AsPC-1, BxPC-3, Panc-1 and MIA PaCa-2 were pret...    »
 
Journal title abbreviation:
Radiol Oncol 
Year:
2017 
Journal volume:
51 
Journal issue:
Pages contribution:
407-414 
Language:
eng 
Fulltext / DOI:
Print-ISSN:
1581-3207 
TUM Institution:
Klinik und Poliklinik für RadioOnkologie und Strahlentherapie