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Document type:
journal article 
Author(s):
Demetz, Gabi; Oostendorp, Robert A J; Boxberg, A Melanie; Sitz, Wibke; Farrell, Eliane; Steppich, Birgit; Steinsiek, Anna-Lena; Rudelius, Martina; Ott, Ilka 
Title:
Overexpression of Insulin-Like Growth Factor-2 in Expanded Endothelial Progenitor Cells Improves Left Ventricular Function in Experimental Myocardial Infarction. 
Abstract:
Insulin-like growth factors (IGFs) are mediators of growth hormone-induced metabolic and anabolic actions, but also regulate cell growth, differentiation, and apoptosis and show beneficial effects in acute myocardial ischemia. Since endothelial progenitor cells (EPCs) improve myocardial function after acute myocardial infarction, we sought to investigate whether overexpression of IGF-2 in expanded EPCs (eEPCs) further contributes to improvement in left ventricular function after myocardial infar...    »
 
Journal title abbreviation:
J Vasc Res 
Year:
2017 
Journal volume:
54 
Journal issue:
Pages contribution:
321-328 
Language:
eng 
Print-ISSN:
1018-1172 
TUM Institution:
Klinik und Poliklinik für Innere Medizin III; Institut für Allgemeine Pathologie und pathologische Anatomie; Klinik für Herz- und Kreislauferkrankungen