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Document type:
journal article 
Author(s):
Nieser, Maike; Henopp, Tobias; Brix, Joachim; Stoß, Laura; Sitek, Barbara; Naboulsi, Wael; Anlauf, Martin; Schlitter, Anna M; Klöppel, G; Gress, Thomas; Moll, R; Bartsch, Detlef K; Heverhagen, Anna E; Knoefel, Wolfram T; Kaemmerer, Daniel; Haybaeck, Johannes; Fend, F; Sperveslage, Jan; Sipos, Bence 
Title:
Loss of Chromosome 18 in Neuroendocrine Tumors of the Small Intestine: The Enigma Remains. 
Abstract:
Neuroendocrine tumors of the small intestine (SI-NETs) exhibit an increasing incidence and high mortality rate. Until now, no fundamental molecular event has been linked to the tumorigenesis and progression of these tumors. Only the loss of chromosome 18 (Chr18) has been shown in up to two thirds of SI-NETs, whereby the significance of this alteration is still not understood. We therefore performed the first comprehensive study to identify Chr18-related events at the genetic, epigenetic and gene...    »
 
Journal title abbreviation:
Neuroendocrinology 
Year:
2017 
Journal volume:
104 
Journal issue:
Pages contribution:
302-312 
Language:
eng 
Print-ISSN:
0028-3835 
TUM Institution:
Institut für Allgemeine Pathologie und pathologische Anatomie