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Document type:
Zeitschriftenaufsatz 
Author(s):
Hao, Yanqi; Colak, Recep; Teyra, Joan; Corbi-Verge, Carles; Ignatchenko, Alexander; Hahne, Hannes; Wilhelm, Mathias; Kuster, Bernhard; Braun, Pascal; Kaida, Daisuke; Kislinger, Thomas; Kim, Philip M. 
Title:
Semi-supervised Learning Predicts Approximately One Third of the Alternative Splicing Isoforms as Functional Proteins 
Abstract:
Alternative splicing acts on transcripts from almost all human multi-exon genes. Notwithstanding its ubiquity, fundamental ramifications of splicing on protein expression remain unresolved. The number and identity of spliced transcripts that form stably folded proteins remain the sources of considerable debate, due largely to low coverage of experimental methods and the resulting absence of negative data. We circumvent this issue by developing a semi-supervised learning algorithm, positive unlab...    »
 
Keywords:
BayBioMS 
Journal title:
Cell Reports 
Year:
2015 
Journal volume:
12 
Journal issue:
Pages contribution:
183-189 
Publisher:
Elsevier BV 
E-ISSN:
2211-1247 
Date of publication:
01.07.2015