User: Guest  Login
Document type:
journal article 
Author(s):
Müller, Stefanie H; Girard, Simon L; Hopfner, Franziska; Merner, Nancy D; Bourassa, Cynthia V; Lorenz, Delia; Clark, Lorraine N; Tittmann, Lukas; Soto-Ortolaza, Alexandra I; Klebe, Stephan; Hallett, Mark; Schneider, Susanne A; Hodgkinson, Colin A; Lieb, Wolfgang; Wszolek, Zbigniew K; Pendziwiat, Manuela; Lorenzo-Betancor, Oswaldo; Poewe, Werner; Ortega-Cubero, Sara; Seppi, Klaus; Rajput, Alex; Hussl, Anna; Rajput, Ali H; Berg, Daniela; Dion, Patrick A; Wurster, Isabel; Shulman, Joshua M; Srulije...    »
 
Title:
Genome-wide association study in essential tremor identifies three new loci. 
Abstract:
We conducted a genome-wide association study of essential tremor, a common movement disorder characterized mainly by a postural and kinetic tremor of the upper extremities. Twin and family history studies show a high heritability for essential tremor. The molecular genetic determinants of essential tremor are unknown. We included 2807 patients and 6441 controls of European descent in our two-stage genome-wide association study. The 59 most significantly disease-associated markers of the discover...    »
 
Journal title abbreviation:
Brain 
Year:
2016 
Journal volume:
139 
Journal issue:
Pt 12 
Pages contribution:
3163-3169 
Language:
eng 
Fulltext / DOI:
Print-ISSN:
0006-8950 
TUM Institution:
Klinik und Poliklinik für Psychosomatische Medizin und Psychotherapie; Lehrstuhl für Neurogenetik