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Document type:
Zeitschriftenaufsatz 
Author(s):
Mueller, Tobias; Fischer, Janett; Gessner, Reinhard; Rosendahl, Jonas; Böhm, Stephan; van Bömmel, Florian; Knop, Viola; Sarrazin, Christoph; Witt, Heiko; Marques, Andreas Mas; Kovacs, Peter; Schleinitz, Dorit; Stumvoll, Michael; Blüher, Matthias; Bugert, Peter; Schott, Eckart; Berg, Thomas 
Title:
Apolipoprotein E allele frequencies in chronic and self-limited hepatitis C suggest a protective effect of APOE4 in the course of hepatitis C virus infection. 
Abstract:
Infectious hepatitis C virus (HCV) particles bind to host lipoproteins such as low-density lipoproteins (LDLs). Low-density lipoprotein receptors (LDLR) have been termed candidate receptors for HCV-LDL complexes. Functional host genetic single nucleotide polymorphisms (SNPs) in the apolipoprotein E (APOE) gene encoding apolipoprotein E (apoE) - a major structural LDL component and natural ligand of LDLR - likely influence the course of HCV infection. We investigated the prevalence of APOE SNPs i...    »
 
Journal title abbreviation:
Liver Int 
Year:
2016 
Journal volume:
36 
Journal issue:
Pages contribution:
1267-74 
Print-ISSN:
1478-3223 
TUM Institution:
Klinik für Ernährungsmedizin