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Document type:
Zeitschriftenaufsatz 
Author(s):
Suess, Barbara; Brockhoff, Anne; Degenhardt, Andreas; Billmayer, Sylvia; Meyerhof, Wolfgang; Hofmann, Thomas 
Title:
Human taste and umami receptor responses to chemosensorica generated by Maillard-type N(2)-alkyl- and N(2)-arylthiomethylation of guanosine 5'-monophosphates 
Abstract:
Structural modification of the exocyclic amino function of guanosine 5'-monophosphate (5'-GMP) by Maillard-type reactions with reducing carbohydrates was recently found to increase the umami-enhancing activity of the nucleotide upon S-N(2)-1-carboxyalkylation and S-N(2)-(1-alkylamino)carbonylalkylation, respectively. Since the presence of sulfur atoms in synthetic N(2)-alkylated nucleotides was reported to be beneficial for sensory activity, a versatile Maillard-type modification of 5'-GMP upon...    »
 
Journal title:
Journal of Agricultural and Food Chemistry 
Year:
2014 
Journal volume:
62 
Journal issue:
47 
Pages contribution:
11429--11440 
Fulltext / DOI:
Print-ISSN:
0021-8561