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Document type:
journal article 
Author(s):
Erlmeier, Franziska; Hartmann, Arndt; Autenrieth, Michael; Wiedemann, Max; Ivanyi, Philipp; Steffens, Sandra; Weichert, Wilko 
Title:
PD-1/PD-L1 expression in chromophobe renal cell carcinoma: An immunological exception? 
Abstract:
Immune checkpoint inhibitors targeting the inhibitory cross talk between tumor and immune cells have been approved for therapy in renal cell carcinoma (RCC). In contrast to clear cell RCC, little is known on PD-1/PD-L1 expression patterns in rarer RCC subtypes. The aim of this study was to evaluate the prevalence, distribution and prognostic impact of PD-1 and PD-L1 expression in chromophobe (ch)RCC. Patients who underwent renal surgery due to chRCC were retrospectively evaluated. Tumor specimen...    »
 
Journal title abbreviation:
Med Oncol 
Year:
2016 
Journal volume:
33 
Journal issue:
11 
Pages contribution:
120 
Language:
eng 
Print-ISSN:
1357-0560 
TUM Institution:
Institut für Allgemeine Pathologie und pathologische Anatomie; Urologische Klinik und Poliklinik