User: Guest  Login
Document type:
journal article 
Author(s):
Kosmidis, M; Dziunycz, P; Suárez-Fariñas, M; Mühleisen, B; Schärer, L; Läuchli, S; Hafner, J; French, LE; Schmidt-Weber, C; Carucci, JA; Hofbauer, GF 
Title:
Immunosuppression affects CD4+ mRNA expression and induces Th2 dominance in the microenvironment of cutaneous squamous cell carcinoma in organ transplant recipients. 
Abstract:
Squamous cell carcinoma (SCC) is the most frequent cancer in organ transplant recipients (OTRs). The immune system plays a major role in the fight against SCC, however, little is known about the local inflammatory response in SCC at all. We analyzed quantity and quality of the perineoplastic inflammatory SCC microenvironment in immunocompetent patients and immmunosuppressed OTRs. RNA expression profile of SCC patients was analyzed for 8 different sets of genes relating to Th1 versus Th2 response...    »
 
Journal title abbreviation:
J Immunother 
Year:
2010 
Journal volume:
33 
Journal issue:
Pages contribution:
538-46 
Language:
eng 
Print-ISSN:
1524-9557 
TUM Institution:
Institut für Molekulare Allergologie und Umweltforschung