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Dokumenttyp:
journal article 
Autor(en):
Vorberg, I; Raines, A; Priola, SA 
Titel:
Acute formation of protease-resistant prion protein does not always lead to persistent scrapie infection in vitro. 
Abstract:
Transmissible spongiform encephalopathies are accompanied by the accumulation of a pathologic isoform of a host-encoded protein, termed prion protein (PrP). Despite the widespread distribution of the cellular isoform of PrP (protease-sensitive PrP; PrP-sen), the disease-associated isoform (protease-resistant PrP; PrP-res) appears to be primarily restricted to cells of the nervous and lymphoreticular systems. In order to study why scrapie infection appears to be restricted to certain cells, we...    »
 
Zeitschriftentitel:
J Biol Chem 
Jahr:
2004 
Band / Volume:
279 
Heft / Issue:
28 
Seitenangaben Beitrag:
29218-25 
Sprache:
eng 
Print-ISSN:
0021-9258 
TUM Einrichtung:
r Virologie