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Dokumenttyp:
journal article 
Autor(en):
Maier, C; Vesovic, Z; Bachmann, N; Herkommer, K; Braun, AK; Surowy, HM; Assum, G; Paiss, T; Vogel, W 
Titel:
Germline mutations of the MSR1 gene in prostate cancer families from Germany. 
Abstract:
The MSR1 gene at 8p22 has been suggested as a candidate gene for hereditary prostate cancer because germline variants have been found to be associated with the disease. Aside from a single nonsense mutation (R293X) that was found repeatedly at low frequencies in several samples, little evidence has been gained by follow-up studies to confirm the gene's relevance for prostate cancer. Prompted by reasonable support for a linkage to 8p22, we sought to determine the mutation spectrum of MSR1 in our...    »
 
Zeitschriftentitel:
Hum Mutat 
Jahr:
2006 
Band / Volume:
27 
Heft / Issue:
Seitenangaben Beitrag:
98-102 
Sprache:
eng 
Print-ISSN:
1059-7794 
TUM Einrichtung:
Urologische Klinik und Poliklinik