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Dokumenttyp:
journal article 
Autor(en):
Hebbring, SJ; Fredriksson, H; White, KA; Maier, C; Ewing, C; McDonnell, SK; Jacobsen, SJ; Cerhan, J; Schaid, DJ; Ikonen, T; Autio, V; Tammela, TL; Herkommer, K; Paiss, T; Vogel, W; Gielzak, M; Sauvageot, J; Schleutker, J; Cooney, KA; Isaacs, W; Thibodeau, SN 
Titel:
Role of the Nijmegen breakage syndrome 1 gene in familial and sporadic prostate cancer. 
Abstract:
The Nijmegen breakage syndrome 1 (NBS1) gene, which participates in DNA double strand break repair, has been postulated to be a susceptibility factor for a number of cancers, including prostate cancer. Numerous mutations have been identified in NBS1, including the founder mutation 657del5. In this study, a number of analyses were done to determine whether mutations in NBS1 are associated with an increased risk for prostate cancer. The frequency of the 657del5 mutation in both familial prostate c...    »
 
Zeitschriftentitel:
Cancer Epidemiol Biomarkers Prev 
Jahr:
2006 
Band / Volume:
15 
Heft / Issue:
Seitenangaben Beitrag:
935-8 
Sprache:
eng 
Print-ISSN:
1055-9965 
TUM Einrichtung:
Urologische Klinik und Poliklinik