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Document type:
journal article 
Author(s):
Hofer, C; van Randenborgh, H; Lehmer, A; Hartung, R; Breul, J 
Title:
Transcutaneous IL-2 uptake mediated by Transfersomes depends on concentration and fractionated application. 
Abstract:
INTRODUCTION: Transfersomes (TF) are new, ultradeformable carriers with characteristics that enable them to penetrate the skin spontaneously. TFs are able to transport noninvasively both low- and high-molecular-weight molecules into the body. MATERIALS AND METHODS: TFs contain phosphatidylcholine and sodium cholate. Recombinant human interleukin-2 (Proleukin, Chiron) was added to the TFs and incubated for 24 h at 4 degrees C. The immunotransfersomes (ITF) were isolated from free interleukin-2 (I...    »
 
Journal title abbreviation:
Cytokine 
Year:
2004 
Journal volume:
25 
Journal issue:
Pages contribution:
141-6 
Language:
eng 
Print-ISSN:
1043-4666 
TUM Institution:
Urologische Klinik und Poliklinik