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Dokumenttyp:
journal article 
Autor(en):
Fiedler, J; Jazbutyte, V; Kirchmaier, BC; Gupta, SK; Lorenzen, J; Hartmann, D; Galuppo, P; Kneitz, S; Pena, JT; Sohn-Lee, C; Loyer, X; Soutschek, J; Brand, T; Tuschl, T; Heineke, J; Martin, U; Schulte-Merker, S; Ertl, G; Engelhardt, S; Bauersachs, J; Thum, T 
Titel:
MicroRNA-24 regulates vascularity after myocardial infarction. 
Abstract:
Myocardial infarction leads to cardiac remodeling and development of heart failure. Insufficient myocardial capillary density after myocardial infarction has been identified as a critical event in this process, although the underlying mechanisms of cardiac angiogenesis are mechanistically not well understood.Here, we show that the small noncoding RNA microRNA-24 (miR-24) is enriched in cardiac endothelial cells and considerably upregulated after cardiac ischemia. MiR-24 induces endothelial cell...    »
 
Zeitschriftentitel:
Circulation 
Jahr:
2011 
Band / Volume:
124 
Heft / Issue:
Seitenangaben Beitrag:
720-30 
Sprache:
eng 
Print-ISSN:
0009-7322 
TUM Einrichtung:
r Pharmakologie und Toxikologie