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Dokumenttyp:
journal article 
Autor(en):
Lacinová, L; Hofmann, F 
Titel:
Ca2+- and voltage-dependent inactivation of the expressed L-type Ca(v)1.2 calcium channel. 
Abstract:
Ca2+-dependent regulation of the ion current through the alpha1Cbeta2aalpha2delta-1 (L-type) calcium channel transiently expressed in HEK 293 cells was investigated using whole cell patch clamp method. Ca2+ or Na+ ions were used as a charge carrier. Intracellular Ca2+ was either buffered by 10 mM EGTA or 200 microM Ca2+ was added into non-buffered intracellular solution. Free intracellular Ca2+ inactivated permanently about 80% of the L-type calcium current. The L-type calcium channel inactivate...    »
 
Zeitschriftentitel:
Arch Biochem Biophys 
Jahr:
2005 
Band / Volume:
437 
Heft / Issue:
Seitenangaben Beitrag:
42-50 
Sprache:
eng 
Print-ISSN:
0003-9861 
TUM Einrichtung:
r Pharmakologie und Toxikologie