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Dokumenttyp:
journal article 
Autor(en):
Dongmo, A; Kamanyi, MA; Tan, PV; Bopelet, M; Vierling, W; Wagner, H 
Titel:
Vasodilating properties of the stem bark extract of Mitragyna ciliata in rats and guinea pigs. 
Abstract:
Mitragyna ciliata is commonly used in traditional medicine for the treatment of inflammation, hypertension, headache, rheumatism, gonorrhoea and broncho-pulmonary diseases. In the present study, the vascular relaxant effect in the rat and guinea-pig was investigated. The extract induced aortic relaxation in a concentration-dependent manner, with an EC(50) of 1.3 and 7 microg/mL for the noradrenaline- and KCl-induced contractions, respectively. The relaxant effect of the extract on KCl-induced co...    »
 
Zeitschriftentitel:
Phytother Res 
Jahr:
2004 
Band / Volume:
18 
Heft / Issue:
Seitenangaben Beitrag:
36-9 
Sprache:
eng 
Print-ISSN:
0951-418X 
TUM Einrichtung:
r Pharmakologie und Toxikologie