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Document type:
journal article 
Author(s):
Höfler, H; Langer, R; Ott, K; Keller, G 
Title:
Prediction of response to neoadjuvant chemotherapy in carcinomas of the upper gastrointestinal tract. 
Abstract:
Multimodal treatment protocols are increasingly employed to improve the survival of patients with locally advanced adenocarcinomas of the upper gastrointestinal tract, however, only 30-40% per year of the patients respond to 5-FU and cisplatin-based neoadjuvant chemotherapy. The goal of our studies is the identification of reliable genetic markers, on the genomic DNA-level, mRNA, or protein level that could predict response of upper gastrointestinal carcinomas prior to neoadjuvant chemotherapy....    »
 
Journal title abbreviation:
Adv Exp Med Biol 
Year:
2006 
Journal volume:
587 
Pages contribution:
115-20 
Language:
eng 
Print-ISSN:
0065-2598 
TUM Institution:
Institut für Allgemeine Pathologie und pathologische Anatomie