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Dokumenttyp:
journal article 
Autor(en):
Sussmann, M; Sarbia, M; Meyer-Kirchrath, J; Nüsing, RM; Schrör, K; Fischer, JW 
Titel:
Induction of hyaluronic acid synthase 2 (HAS2) in human vascular smooth muscle cells by vasodilatory prostaglandins. 
Abstract:
Hyaluronic acid (HA) is a prominent constituent of the extracellular matrix of atherosclerotic vascular lesions in humans known to modulate vascular smooth muscle phenotype. The regulation of HA synthesis by vasodilatory prostaglandins was analyzed in human arterial smooth muscle cells (SMCs). The prostacyclin analogue, iloprost (100 nmol/L), markedly increased pericellular formation of HA coats and HA secretion into the cell culture medium in human arterial SMCs (8.7+/-1.6-fold). Expression of...    »
 
Zeitschriftentitel:
Circ Res 
Jahr:
2004 
Band / Volume:
94 
Heft / Issue:
Seitenangaben Beitrag:
592-600 
Sprache:
eng 
Print-ISSN:
0009-7330 
TUM Einrichtung:
r Allgemeine Pathologie und pathologische Anatomie