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Dokumenttyp:
journal article 
Autor(en):
Jouyban, A; Shayanfar, A; Panahi-Azar, V; Soleymani, J; Yousefi, BH; Acree, WE; York, P 
Titel:
Solubility prediction of drugs in mixed solvents using partial solubility parameters. 
Abstract:
Solubility of drugs in binary and ternary solvent mixtures composed of water and pharmaceutical cosolvents at different temperatures were predicted using the Jouyban-Acree model and a combination of partial solubility parameters as interaction descriptors in the solution. The generally trained version of the model produced the overall mean percentage deviation values for the back-calculated solubility of drugs in binary solvents of 34.3% and the predicted solubilities in ternary solvent mixtures...    »
 
Zeitschriftentitel:
J Pharm Sci 
Jahr:
2011 
Band / Volume:
100 
Heft / Issue:
10 
Seitenangaben Beitrag:
4368-82 
Sprache:
eng 
Print-ISSN:
0022-3549 
TUM Einrichtung:
Nuklearmedizinische Klinik und Poliklinik