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Dokumenttyp:
journal article 
Autor(en):
Schwaiger, M; Schübeler, D 
Titel:
A question of timing: emerging links between transcription and replication. 
Abstract:
The coordination of transcription and timing of DNA replication during the S phase of the cell cycle has recently been studied chromosome-wide in high resolution. This revealed that in the complex genome of higher eukaryotes actively transcribed genes are more likely to replicate early in S phase. Dynamic changes in chromatin structure and nuclear organization appear to provide the underlying mechanism to link transcription and replication. A possible evolutionary benefit for this connection mig...    »
 
Zeitschriftentitel:
Curr Opin Genet Dev 
Jahr:
2006 
Band / Volume:
16 
Heft / Issue:
Seitenangaben Beitrag:
177-83 
Sprache:
eng 
Print-ISSN:
0959-437X 
TUM Einrichtung:
Nuklearmedizinische Klinik und Poliklinik