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- Document type:
- Clinical Trial; Journal Article; Validation Studies; Article
- Author(s):
- Yoneyama, T; Matsunari, I; Kanayama, S; Matsudaira, M; Nakajima, K; Taki, J; Nekolla, SG; Hisada, K; Tonami, N
- Title:
- Accuracy of cardiac PET imaging using post-injection transmission scan.
- Abstract:
- The purpose of this study was to investigate the accuracy of cardiac PET with post-injection transmission scans. METHODS: We performed a phantom study using 18F solution as well as 13N-ammonia PET study of ten patients. The average activities of no myocardial defect phantom model were estimated, and myocardial defect sizes of 12 phantom models were measured by pre- and post-injection transmission methods at various 18F activities. In 13N-ammonia PET at rest and during adenosine triphosphate (ATP) stress studies, measured defect sizes were compared between both methods. RESULTS: The ratios of average activity estimated by both methods (post/pre value) were almost 1.00 at each 18F activity and segment. Measured defect sizes by both methods showed an excellent correlation with true defect sizes (r = 0.98, p < 0.01 for pre vs. true value: r = 0.98, p < 0.01 for post vs. true value). The mean absolute errors of measurements were minimal up to 3.5% LV, and were similar between both methods. In 13N-ammonia PET, measured defect sizes by both methods also showed a good correlation (r = 0.97, p < 0.01). CONCLUSION: The results indicate that cardiac PET imaging with post-injection transmission scan provides information on myocardial tracer activity as well as myocardial defect size as does conventional pre-injection transmission method.
- Journal title abbreviation:
- Ann Nucl Med
- Year:
- 2005
- Journal volume:
- 19
- Journal issue:
- 2
- Pages contribution:
- 83-9
- Language:
- eng
- Pubmed ID:
- http://view.ncbi.nlm.nih.gov/pubmed/15909486
- Print-ISSN:
- 0914-7187
- TUM Institution:
- Klinik und Poliklinik für Nuklearmedizin
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