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Dokumenttyp:
journal article 
Autor(en):
Spuentrup, E; Buecker, A; Katoh, M; Wiethoff, AJ; Parsons, EC; Botnar, RM; Weisskoff, RM; Graham, PB; Manning, WJ; Günther, RW 
Titel:
Molecular magnetic resonance imaging of coronary thrombosis and pulmonary emboli with a novel fibrin-targeted contrast agent. 
Abstract:
BACKGROUND: The differential diagnosis of acute chest pain is challenging, especially in patients with normal ECG findings, and may include coronary thrombosis or pulmonary emboli. The aim of this study was to investigate the novel fibrin-specific contrast agent EP-2104R for molecular targeted MR imaging of coronary thrombosis and pulmonary emboli. METHODS AND RESULTS: Fresh clots were engineered ex vivo from human blood and delivered in the lungs and coronary arteries of 7 swine. Subsequent mol...    »
 
Zeitschriftentitel:
Circulation 
Jahr:
2005 
Band / Volume:
111 
Heft / Issue:
11 
Seitenangaben Beitrag:
1377-82 
Sprache:
eng 
Print-ISSN:
0009-7322 
TUM Einrichtung:
Nuklearmedizinische Klinik und Poliklinik