User: Guest  Login
Document type:
journal article 
Author(s):
Kummer, TT; Misgeld, T; Sanes, JR 
Title:
Assembly of the postsynaptic membrane at the neuromuscular junction: paradigm lost. 
Abstract:
Studies of the vertebrate skeletal neuromuscular junction led to an influential model of how neurotransmitter receptors accumulate in the postsynaptic membrane. In this model, motor axons organize postsynaptic development by secreting neuregulin to induce acetylcholine receptor gene transcription in specialized subsynaptic nuclei, agrin to cluster diffuse receptors in the postsynaptic membrane, and acetylcholine to evoke electrical activity that promotes synaptic maturation. However, new studies...    »
 
Journal title abbreviation:
Curr Opin Neurobiol 
Year:
2006 
Journal volume:
16 
Journal issue:
Pages contribution:
74-82 
Language:
eng 
Print-ISSN:
0959-4388 
TUM Institution:
r Neurowissenschaften