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Document type:
journal article 
Author(s):
Feil, S; Zimmermann, P; Knorn, A; Brummer, S; Schlossmann, J; Hofmann, F; Feil, R 
Title:
Distribution of cGMP-dependent protein kinase type I and its isoforms in the mouse brain and retina. 
Abstract:
Nitric oxide (NO) modulates a variety of processes in the mammalian brain, but the mechanisms of neuronal NO signaling are poorly understood. In the periphery, many effects of NO are mediated via the generation of the second messenger cyclic guanosine-3',5'-monophosphate (cGMP) and activation of the cGMP-dependent protein kinase type I (cGKI). However, previous studies suggested that the expression of cGKI in the nervous system is rather restricted, thus, questioning the functional significance...    »
 
Journal title abbreviation:
Neuroscience 
Year:
2005 
Journal volume:
135 
Journal issue:
Pages contribution:
863-8 
Language:
eng 
Print-ISSN:
0306-4522 
TUM Institution:
Institut für Pharmakologie und Toxikologie