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Document type:
journal article 
Author(s):
Hartmann, J; Henning, HA; Konnerth, A 
Title:
mGluR1/TRPC3-mediated Synaptic Transmission and Calcium Signaling in Mammalian Central Neurons. 
Abstract:
Metabotropic glutamate receptors type 1 (mGluR1s) are required for a normal function of the mammalian brain. They are particularly important for synaptic signaling and plasticity in the cerebellum. Unlike ionotropic glutamate receptors that mediate rapid synaptic transmission, mGluR1s produce in cerebellar Purkinje cells a complex postsynaptic response consisting of two distinct signal components, namely a local dendritic calcium signal and a slow excitatory postsynaptic potential. The basic mec...    »
 
Journal title abbreviation:
Cold Spring Harb Perspect Biol 
Year:
2011 
Journal volume:
Journal issue:
Language:
eng 
TUM Institution:
Institut für Neurowissenschaften