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Document type:
journal article 
Author(s):
Boecker, H; Sprenger, T; Henriksen, G; Toelle, TR; Spilker, ME 
Title:
Optimal duration of PET studies with 18F-fluoroethyl-diprenorphine. 
Abstract:
The tracer 6-O-(2-(18)F-fluoroethyl)-6-O-desmethyldiprenorphine (18F-FDPN) provides enhanced flexibility to PET studies of the opioidergic system because the label has a longer half-life than the label of 11C-diprenorphine. Here we evaluated the ideal length of PET studies with 18F-FDPN. METHODS: 18F-FDPN binding kinetics were quantified with protocols of different lengths by use of a 1-tissue or a 2-tissue compartment model for different volumes of interest. Furthermore, the effects of scanning...    »
 
Journal title abbreviation:
J Nucl Med 
Year:
2005 
Journal volume:
46 
Journal issue:
12 
Pages contribution:
2092-6 
Language:
eng 
Print-ISSN:
0161-5505 
TUM Institution:
Neurologische Klinik und Poliklinik; Nuklearmedizinische Klinik und Poliklinik