In industrialized countries, stroke is a leading cause of death. Of those patients that survive a stroke, many will have to cope with long-term disability. In addition to the effective diagnosis and therapy of known cardiovascular risk factors for primary and secondary prevention strategies, platelet inhibitors are important for the secondary prevention of stroke. Apart from aspirin, the platelet inhibitors clopidogrel and the combination of aspirin and dipyridamole are available. In the following paper we present an overview on the current status of modern differential therapy wit the different platelet inhibitors. Possible therapeutic strategies in more complex clinical constellations such as the persistent foramen ovale, intracranial stenosis were described in more detail and possible indications for the combined application of platelet inhibitors are discussed.     «

In industrialized countries, stroke is a leading cause of death. Of those patients that survive a stroke, many will have to cope with long-term disability. In addition to the effective diagnosis and therapy of known cardiovascular risk factors for primary and secondary prevention strategies, platelet inhibitors are important for the secondary prevention of stroke. Apart from aspirin, the platelet inhibitors clopidogrel and the combination of aspirin and dipyridamole are available. In the followi...     »