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Document type:
journal article 
Author(s):
Lutz, J; Zou, H; Liu, S; Antus, B; Heemann, U 
Title:
Apoptosis and treatment of chronic allograft nephropathy with everolimus. 
Abstract:
BACKGROUND: Chronic allograft nephropathy (CAN) is responsible for most cases of late kidney allograft loss. However, no effective treatment is available so far. Everolimus (RAD) (40-O [2-hydroxyethyl] rapamycin) is a new immunosuppressive agent with antiproliferative and apoptosis-enhancing effects. We asked whether everolimus can ameliorate CAN even at advanced stages, whether everolimus treatment affects the level of growth factor mRNA, and whether everolimus treatment affects the number of a...    »
 
Journal title abbreviation:
Transplantation 
Year:
2003 
Journal volume:
76 
Journal issue:
Pages contribution:
508-15 
Language:
eng 
Print-ISSN:
0041-1337 
TUM Institution:
Abteilung für Nephrologie