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Document type:
journal article 
Author(s):
Tischer, T; Schieker, M; Stengele, M; Pautke, C; Neth, P; Jochum, M; Mutschler, W; Milz, S 
Title:
[3D-Culturing of human osteoblastic cells with vessel like nutrient supply] 
Abstract:
AIM: The treatment of large, critical-size bone defects is a major therapeutic problem in orthopaedic and reconstructive surgery. The engineering of bone tissue could be used to replace lost bone mass. However, scaffolds seeded with vital cells and cultured in vitro suffer from poor oxygen and nutrient supply centrally, when the constructs exceed a critical volume. Therefore, we have established an osteoblastic cell culture in a new 3D-culture chamber with an artificial, vessel-like central memb...    »
 
Journal title abbreviation:
Z Orthop Ihre Grenzgeb 
Year:
2004 
Journal volume:
142 
Journal issue:
Pages contribution:
344-9 
Language:
de 
Print-ISSN:
0044-3220 
TUM Institution:
die; r Mund-, Kiefer- und Gesichtschirurgie