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Dokumenttyp:
journal article 
Autor(en):
Wagner, H 
Titel:
New vistas on TLR9 activation. 
Abstract:
Together with other reports, evidence published in this issue of the European Journal of Immunology by Avalos and Ploegh (Eur. J. Immunol. 2011. 41: 2820-2827) implies that trafficking of TLR9 from the ER to endolysosomal compartments, which is aided by the transmembrane UNC93B1 ER protein, is followed by proteolytic cleavage of the TLR9 ectodomain (TLR9ecto). Furthermore, Avalos and Ploegh elegantly show that RAW 264.7 macrophages stably expressing tagged TLR9 display significant amounts of cle...    »
 
Zeitschriftentitel:
Eur J Immunol 
Jahr:
2011 
Band / Volume:
41 
Heft / Issue:
10 
Seitenangaben Beitrag:
2814-6 
Sprache:
eng 
Print-ISSN:
0014-2980 
TUM Einrichtung:
r Medizinische Mikrobiologie, Immunologie und Hygiene