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Dokumenttyp:
journal article 
Autor(en):
von Meyenn, F; Schaefer, M; Weighardt, H; Bauer, S; Kirschning, CJ; Wagner, H; Sparwasser, T 
Titel:
Toll-like receptor 9 contributes to recognition of Mycobacterium bovis Bacillus Calmette-Guérin by Flt3-ligand generated dendritic cells. 
Abstract:
Recognition of mycobacteria by the innate immune system is essential for the development of an adaptive immune response. Mycobacterial antigens stimulate antigen presenting cells (APCs) through distinct Toll-like receptors (TLRs) resulting in rapid activation of the innate immune system. The role of TLRs during infection with Mycobacterium bovis Bacillus Calmette-Guérin (BCG) has been evaluated for TLR2 and TLR4 only. Surprisingly, despite the fact that immune stimulatory CpG-motifs have been or...    »
 
Zeitschriftentitel:
Immunobiology 
Jahr:
2006 
Band / Volume:
211 
Heft / Issue:
6-8 
Seitenangaben Beitrag:
557-65 
Sprache:
eng 
Print-ISSN:
0171-2985 
TUM Einrichtung:
r Medizinische Mikrobiologie, Immunologie und Hygiene