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Dokumenttyp:
journal article 
Autor(en):
Panthel, K; Meinel, KM; Sevil Domènech, VE; Geginat, G; Linkemann, K; Busch, DH; Rüssmann, H 
Titel:
Prophylactic anti-tumor immunity against a murine fibrosarcoma triggered by the Salmonella type III secretion system. 
Abstract:
The potential of an attenuated Salmonella enterica serovar Typhimurium strain as a prophylactic anti-tumor vaccine against the murine fibrosarcoma WEHI 164 was evaluated. Tumor cells were transfected with the DNA sequence encoding the MHC class I-restricted peptide p60(217-225) from Listeria monocytogenes. BALB/c mice received a single orogastric immunization with Salmonella that translocates a chimeric p60 protein via its type III secretion system. Mice were subsequently challenged subcutaneous...    »
 
Zeitschriftentitel:
Microbes Infect 
Jahr:
2006 
Band / Volume:
Heft / Issue:
9-10 
Seitenangaben Beitrag:
2539-46 
Sprache:
eng 
Print-ISSN:
1286-4579 
TUM Einrichtung:
r Medizinische Mikrobiologie, Immunologie und Hygiene