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Dokumenttyp:
journal article 
Autor(en):
Hellebrand, E; Mautner, J; Reisbach, G; Nimmerjahn, F; Hallek, M; Mocikat, R; Hammerschmidt, W 
Titel:
Epstein-Barr virus vector-mediated gene transfer into human B cells: potential for antitumor vaccination. 
Abstract:
The efficient gene transfer of immunostimulatory cytokines into autologous tumor cells or the transfer of tumor-associated antigens into professional antigen-presenting cells is a prerequisite for many immunotherapeutic approaches. In particular with B cells, the efficiency of gene uptake is one of the limiting factors in cell-based vaccine strategies, since normal and malignant human B cells are commonly refractory to transducing gene vectors. Due to its natural tropism for human B cells, Epste...    »
 
Zeitschriftentitel:
Gene Ther 
Jahr:
2006 
Band / Volume:
13 
Heft / Issue:
Seitenangaben Beitrag:
150-62 
Sprache:
eng 
Print-ISSN:
0969-7128 
TUM Einrichtung:
Kinderklinik und Poliklinik